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Sono molteplici le sfide che la medicina alleata al genere umano si trova costretta ad accettare, trovata la cura di una patologia generalmente ecco apparire una nuova sfida, una nuova malattia si presenta prepotente all’orizzonte mietendo vittime al suo arrivo, quindi si ricomincia da capo cercando una nuova cura. Purtroppo tutto questo è frutto del destino umano, del vivere in un pianeta dove tutto cambia, tutto si modifica nel bene e nel male, un pianeta sul quale l’uomo, se desidera vivere si trova costretto necessariamente a combattere una guerra infinita, la famosa guerra del bene contro il male, in cui l’umanità è costretta a trovarsi sempre in perfetto equilibrio…..RICERCA MEDICA. Ancora una volta la ricerca italiana eccelle in campo medico. Secondo questa news si presenta un’ importante scoperta che potrà aiutare l’umanità del prossimo futuro nella lotta contro i tumori, uno dei mali che maggiormente affliggono la nostra società, i quali a mia opinione provocano il maggior tasso di mortalità del terzo millennio. Proprio in questi giorni sempre stando a questa news, sarebbe stata individuata una particolare  proteina che permetterebbe la crescita dei tumori. La conoscenza approfondita di questa proteina aiuterebbe a bloccare le cellule del sistema immunitario chiamate “macrofagi”, cellule che si sarebbero rivelate fra le migliori alleate dei famigerati tumori. Veramente una grande scoperta ed un balzo in avanti sulla lotta contro questa terribile malattia, una scoperta pubblicata sulla rivista “Pnas” dell’Accademia delle Scienze degli Stati Uniti. La ricerca è stata condotta da Emanuele Giurisato del Dipartimento di Medicina molecolare e dello sviluppo dell’Università di Siena assieme alla ricercatrice dell’Università di Manchester Caty Tournier ed a William Vermi dell’Università di Brescia. Queste particolari cellule, i macrofagi, sono chiamate anche cellule spazzino (relativamente al sistema immunitario), tuttavia si è capito che esse possono essere “riprogrammate” quando interferiscono con il micro ambiente che si viene a creare quando le cellule sane mutano in tumorali. In questo particolare momento i macrofagi che avrebbero acquisito una sorta di nuova identità (resa possibile dalla proteina ERK3) diventerebbero alleati dei tumori aiutandoli nientemeno che nella loro crescita. Detto questo si è scoperto che la proteina ERK3 potrebbe divenire bersaglio dei farmaci futuri. I test effettuati sui ratti hanno risposto positivamente al blocco dei tumori quindi eliminando la proteina ERK3 sarà possibile ridurre il numero dei macrofagi bloccandone di conseguenza l’azione. Ecco le parole dei ricercatori:

(ANSA) -“Siamo riusciti a dimostrare come nei topi la crescita di carcinoma si sia ridotta in assenza della proteina ERK-5, mentre contemporaneamente si sia creata una situazione infiammatoria anti-tumorale”, ha rilevato Giurisato. “Questi risultati – ha aggiunto – accrescono la possibilità che andare a colpire i macrofagi pre-tumorali attraverso una terapia che sopprima la proteina ERK-5 costituisca una nuova strategia per future cure anticancro”-.

 

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